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Amino acid sequences of human SCA-2 (hSCA-2), human PSCA (hPSCA), and mouse PSCA (mPSCA). Shaded regions highlight conserved amino acids, and conserved cysteines are indicated by boldface type. Four predicted N-glycosylation sites in PSCA are indicated by asterisks. The underlined amino acids at the beginning and end of the protein represent amino-terminal hydrophobic signal sequences and C-terminal GPI-anchoring sequences, respectively.
