Table 3.
The ΔF508 allele of CFTR: Tests of hypotheses
| Hypthesis | 27 loci
|
Medial 21 loci
|
13 regions
|
|||
|---|---|---|---|---|---|---|
| χ2 | df | χ2 | df | χ2 | df | |
| M = 1, L = 0, S = .88 | 29.44 | 26 | 22.69 | 20 | 12.54 | 12 |
| M = 1, L = .050, S = .88 | 29.47 | 26 | 22.71 | 20 | 12.42 | 12 |
| M = 1, L = 0 | 24.06 | 25 | 18.92 | 19 | 9.60 | 11 |
| M = 1, L = .050 | 24.20 | 25 | 18.99 | 19 | 9.58 | 11 |
| M = 1 | 24.06 | 24 | 18.92 | 18 | 9.58 | 10 |
| M = .99 | 24.96 | 24 | 19.40 | 18 | 9.63 | 10 |
Parameters fixed by hypothesis are given. Values of estimated parameters (ɛ, S, and L) are not shown. χ2, goodness of fit to Malecot model with df (degrees of freedom).