Table 2.
Differences in nucleotide and amino acid sequences between Langat virus strains TP21 and E5
| Strain
|
E5
|
TP21
|
||
|---|---|---|---|---|
| Gene | NT | AA | NT | AA |
| C | C371 | Pro80 | A | Thr |
| A461 | Ile110 | C | Leu | |
| preM | U514 | G | ||
| E | A1327 | C | ||
| A1342 | G | |||
| C1436 | Thr435 | C/U | Thr/Ile | |
| U1567 | A | |||
| A1823 | Ser564 | G | Gly | |
| C1968 | Ser612 | U | Phe | |
| G2135 | Asp668 | A | Asn | |
| NS1 | A3008 | Met960 | G | Val |
| U3403 | C | |||
| NS2A | G3635 | Ala1168 | C | Pro |
| C3637 | G | |||
| A3964 | G | |||
| NS3 | G4662 | Ser1510 | A | Asn |
| A5339 | Tyr1736 | U | Phe | |
| U5374 | C | |||
| C5546 | Leu1805 | U | Phe | |
NT or AA is indicated nucleotide or amino acid residue at indicated position of LGT E5 genome of polyprotein. Polyprotein sequence of strain TP21 determined in this study differed from that of the TP21 polyprotein published earlier (7, 16). Instead of Glu-152, Ser-564, Ser-612, Met-960, Ala-1168, Ile-2149, Val-2357, Ser-2775, Ala-2921, Cys-3157, and Val-3158, we found a Asp, Gly, Phe, Val, Pro, Met, Ile, Cys, Gly, Trp, or Leu residue, respectively.