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. 1998 Feb 17;95(4):1776–1781. doi: 10.1073/pnas.95.4.1776

Figure 5.

Figure 5

Inhibition of glycogenolysis by CP-91149 in isolated rat hepatocytes. Isolated rat hepatocytes were preincubated with (A) 100 μM CP-91149 or DMSO or (B) 1–100 μM CP-91149 or DMSO for 5 min, then in the absence (filled bars) or presence (open bars) of 0.3 nM GGN for 60 min in buffer containing 7.5 mM glucose, followed by glycogen determination. Results (μmol/g) are the mean ± SD of triplicate determinations. ∗∗, P < 0.01; ∗∗∗, P < 0.001 between treatment (GGN, CP-91149) vs. control (no GGN); †, P < 0.05; ‡, P < 0.01; §, P < 0.001 between CP-91149 + GGN vs. control + GGN.