Table 2.

Effect of CP-91149 on ¹⁴C-glycogen content and plasma glucose concentration in ob/ob mice

Group	14C-glycogen, dpm/mg	Plasma glucose concentration, mg/dl
Vehicle	17.0 ± 2.6	235 ± 21
CP-91149	51.6 ± 8.4**	134 ±  7***

In vivo ¹⁴C-liver glycogenolysis was determined as described. Plasma glucose concentration and live ¹⁴C-glycogen content were determined 3 h after dosing. Values are the mean ± SEM for n = 9-10 mice from a representative experiment. ∗∗, P < 0.01; ∗∗∗, P < 0.001 between CP-91149 and vehicle-treated groups.