Table 2.

Clinical and parasitological efficacy of the five antimalarial drug combinations

	Artesunate-amodiaquine N = 360	Artesunate-mefloquine N = 145	Artemether-lumefantrine (four doses) N = 140	Artemether-lumefantrine (six doses) N = 149	Amodiaquine-sulphadoxine-pyrimethamine N = 161
Parasitological failure, day14	0%	0%	0%	0%	0%
Clinical failure, day14 (n)	0%	0%	0.7% (1)	0%	0%
ACPR, day 14	100%	100%	99.3%	0%	100%
Gametocyte carriage, day 14	0%	0%	0%	3%	0%
Parasitological failure, day 21	0%	0%	0%	0%	0%
Clinical failure, day 21 (n)	1.4% (5)	0.7% (1)	3.6% (5)	0%	0.6% (1)
ACPR, day 21	98.6%	99.3%	96.4%	0%	99.4%
Gametocyte carriage, day 21	0%	0%	0%	0%	0%
Parasitological failure, day 28 (n)	0.8% (3)	0%	1.4% (2)	0%	0%
Clinical failure, day 28 (n)	0.3% (1)	1.4% (2)	11.4% (16)	0%	0.6% (1)
ACPR, day 28	97.5%	97.9%	82.8%	0%	98.7%
Gametocyte carriage, day 28	0%	0%	0%	0%	0%
ACPR, day 28 after PCR	100%	100%	96.4%	100%	100%
ACPR, day 42 (30% of patients)	100%	100%	100%	100%	100%