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Thermodynamic Distribution of Experimental Sequences. Empirical thermodynamic distributions of experimental antisense sequences. The curves represent the distribution of Gibbs free energy (dG) for the effective (green) and ineffective (red) antisense sequences. The average dG for the effective sequences (-24.04 kcal/mol) was significantly more negative than the average dG for the ineffective sequences (-22.80 kcal/mol).
