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. 2007 Jun 6;35(12):4007–4017. doi: 10.1093/nar/gkm245

Figure 1.

Figure 1.

Kt-42+rGAC rRNA system. (A) Base pairing in the simulated Kt-42+rGAC system (helices 42–44 from the 23S rRNA of H. marismortui) using standard nomenclature (54). The two flexible regions are marked as rectangles and the individual helices are marked as H42, H43 and H44. Strand connectivity is not highlighted to keep the figure readable. (B) Secondary structure of the Kt-42+rGAC. (C) Schematic representation of the Kt-42+rGAC showing its modularity with five consecutive segments (C-stem, Hinge1, NC-stem, Hinge2 and Head) with very distinct intrinsic mechanical properties and dynamics (see the text). Two flexible Hinges (circles) link three rigid segments (C-stem, NC-stem and Head). Arrows indicate the direction of preferred motions at both Hinges.