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Base tetrad A1207/G1160 … G1190/C1186 at the helix 42/rGAC junction. The overall X-ray geometry (A), the trans H/SE A1207/G1160 base pair with dynamical water insertion (B left), the trans WC/WC G1190/C1186 base pair assisted either by water or ion (B right) and the unusual G1190/G1160 base pair (X-ray structure, C left). A similar A1192/C1182 contact is shown (C right). Extended analysis of base pairing dynamics is given in Supplementary Data.
