Table 2.
Susceptibility of strains FA19 and KH14 to antibacterial peptides: MGICs of test strains under high and low salt
| High salt*
|
Low salt†
|
|||
|---|---|---|---|---|
| FA19 | KH14 | FA19 | KH14 | |
| PG-1 | 10 | 1.25 | 2.5 | 0.3 |
| PC-8 | >100 | 100 | 100 | 25 |
| LL-37 | >100 | 3.12 | 6.25 | 0.75 |
| HNP 2 | >200 | >200 | >200 | >200 |
| NP 2 | >200 | >200 | >200 | >200 |
| TP-1 | 5 | 1.25 | 0.62 | 0.62 |
All values are expressed in μg/ml as determined by the growth inhibition assay described in text. All values are from a single assay that are representative of two-three independent determinations. The concentrations in μg/ml of each peptide tested were: PG-1, 20-0.15; PC-8, 100-1.56; LL-37, 100-0.375; NP 2 and HNP 2, 200-6.25; TP-1, 10-0.15.
*High salt = 76.5 mM NaCl.
†
Low salt = 7.65 mM NaCl in the incubation media.