Table 1.
Subject | Voxels
|
Hypercapnia
|
Photic stimulation
|
||||
---|---|---|---|---|---|---|---|
Total 225 | BH | FH | M | BS | FS | rCMRO2 | |
1A | 23 | 1.020 ± 0.001 | 1.169 ± 0.001 | 0.11 ± 0.01 | 1.016 ± 0.001 | 1.35 ± 0.02 | 1.14 ± 0.01 |
1B | 25 | 1.009 ± 0.001 | 1.058 ± 0.008 | 0.09 ± 0.01 | 1.014 ± 0.001 | 1.40 ± 0.05 | 1.19 ± 0.03 |
2A | 12 | 1.025 ± 0.001 | 1.27± 0.05 | 0.06 ± 0.02 | 1.021 ± 0.001 | 1.55 ± 0.07 | 1.17 ± 0.04 |
2B | 27 | 1.024 ± 0.002 | 1.26 ± 0.03 | 0.08 ± 0.02 | 1.021 ± 0.001 | 1.46 ± 0.03 | 1.16 ± 0.02 |
3A | 32 | 1.0218 ± 0.007 | 1.15 ± 0.01 | 0.12 ± 0.01 | 1.0204 ± 0.0008 | 1.38 ± 0.03 | 1.16 ± 0.02 |
3B* | 28 | 1.0133 ± 0.0006 | 1.21 ± 0.01 | 0.06 ± 0.003 | 1.019 ± 0.001 | 1.54 ± 0.04 | 1.12 ± 0.02 |
4A | 27 | 1.014 ± 0.002 | 1.11 ± 0.02 | 0.06 ± 0.02 | 1.022 ± 0.002 | 1.47 ± 0.03 | 1.16 ± 0.03 |
4B* | 10 | 1.010 ± 0.002 | 1.08 ± 0.04 | 0.06 ± 0.02 | 1.005 ± 0.001 | 1.28 ± 0.04 | 1.18 ± 0.02 |
5A | 21 | 1.0222 ± 0.0004 | 1.17 ± 0.02 | 0.09 ± 0.01 | 1.016 ± 0.001 | 1.35 ± 0.04 | 1.15 ± 0.02 |
5B | 20 | 1.017 ± 0.001 | 1.29 ± 0.02 | 0.053 ± 0.005 | 1.022 ± 0.002 | 1.67 ± 0.06 | 1.13 ± 0.03 |
Mean ± SE | 1.018 ± 0.002 | 1.18 ± 0.03 | 0.079 ± 0.007 | 1.017 ± 0.005 | 1.45 ± 0.04 | 1.16 ± 0.01 | |
SD(exp) | 0.00572 | 0.0807 | 0.02355 | 0.005421 | 0.1173 | 0.02109 | |
SD(sim) | 0.00073 | 0.0107 | 0.00550 | 0.000577 | 0.0273 | 0.02530 | |
Var ratio | 61 | 57 | 18 | 88 | 18 | 0.7† |
Least squares estimates ± standard errors in primary visual cortex. BH and FH, BOLD and CBF hypercapnia divided by baseline; BS and FS, BOLD and CBF photic stimulation divided by baseline; M, BOLD sensitivity calibration parameter; rCMRO2, change in cerebral metabolic rate for oxygen.
Long duration (5 min) stimulus paradigm; not averaged into Fig. 2.
rCMRO2 is the only estimate without measurable inter-trial variance compared with Monte Carlo simulated measurement noise, SD(sim) (α = 0.7). The remainder have significant variance over measurement noise (P < 0.001; F = 10 at α = 0.001, n1 = 9, n2 = 9).