Table 1.
Morphometric analysis of p75NTR-immunoreactive neurons
| Group | Medial septum
|
Nucleus basalis
|
||
|---|---|---|---|---|
| Cell counts | Cell volume, μm3 | Cell counts | Cell volume, μm3 | |
| Adult (12 months old) | 5,269 ± 355 | 7,381 ± 256 | 6,126 ± 271 | 11,332 ± 604 |
| Int+con-graft (aged) | 5,084 ± 292 | 5,554 ± 463*† | 6,418 ± 318 | 8,640 ± 293‡ |
| NGF-graft (aged) | 4,924 ± 314 | 7,847 ± 662 | 6,082 ± 473 | 12,193 ± 433 |
Intact and control-graft groups did not differ in any of the measured parameters (P > 0.05). Medial septum: cell counts, intact = 5,451 ± 684, control-graft = 4,810 ± 488 cells; volume, intact = 5,524 ± 1,117 μm3, control-graft = 5,576 ± 356 μm3. Nucleus basalis: cell counts, intact = 6,361 ± 671 cells, control-graft = 6,462 ± 359 cells; volume, intact = 8,271 ± 582 μm3, control-graft = 8,918 ± 269 μm3.
*
Different from adult, P < 0.05, one-way ANOVA post-hoc Fisher PLSD.
†
Different from NGF-graft, P < 0.05, one-way ANOVA post-hoc Scheffe F-test.
‡
Different from adult and NGF-graft, P < 0.05, one-way ANOVA post-hoc Scheffe F-test.