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. 1992 Aug;36(8):1770–1772. doi: 10.1128/aac.36.8.1770

Long-term tolerance and efficacy of 3'-azidothymidine and 3'-fluorothymidine treatment of asymptomatic monkeys infected with simian immunodeficiency virus.

D Böttiger 1, L Ståhle 1, S L Li 1, B Oberg 1
PMCID: PMC192045  PMID: 1416863

Abstract

Macaques chronically infected with simian immunodeficiency virus were treated with zidovudine (20 mg/kg of body weight per day for 9 weeks) or 3'-fluorothymidine (5 mg/kg of body weight per day for 9 weeks or three doses of 2 mg/kg per day for 24 days). Hematological changes in the treated animals included macrocytic anemia and leukopenia. Determination of antiviral effects in this model requires improved assay methods.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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