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. Author manuscript; available in PMC: 2007 Jul 16.
Published in final edited form as: Invest Ophthalmol Vis Sci. 2007 Feb;48(2):652–660. doi: 10.1167/iovs.06-1007

Figure 3.

Figure 3

Effect of altered intracellular cAMP levels on UV irradiation–induced JNK activation. (A) Effect of 8-cpt-cAMP on UV irradiation–induced JNK phosphorylation. (B) Effect of forskolin on UV irradiation–induced JNK phosphorylation. (C) Effect of Rp-cpt-cAMP on UV irradiation–induced JNK phosphorylation. Intracellular cMAP levels were altered by exposure of HCE cells to 8-cpt-cAMP, forskolin or Rp-cpt-cAMP at indicated concentrations in the absence and presence of 5 mM caffeine 30 minutes before UV irradiation. HCE cells were harvested 15 minutes after UV irradiation for Western blot analysis.