Brain regions relevant to the addictions (see text box for description of regions). Right panel represents an MRI of the sagittal brain (from SPM96) at Talairach coordinates x = 4–16; left panel, at x = 34–46. Each Talaraich coordinate represents a one mm MRI sagittal slice, and 13 slices were averaged for each displayed image. Amyg, amygdala; ant cing, anterior cingulate; DLPFC, dorsolateral prefrontal cortex; LOFC, lateral orbitofrontal cortex; MOFC, medial orbitofrontal cortex (ventromedial cortex); NAc, nucleus accumbens; VTA, ventral tegmental area. The MRI template was obtained from SPM96-MRI.