Table 1.
Hospitalization and mortality rates among HIV-infected children, by 24-week interval after initiation of HAART.
| Variable | 0–24 weeks | 25–48 weeks | 49–72 weeks | 73–96 weeks | 97–120 weeks | 120–144 weeks |
|---|---|---|---|---|---|---|
| Patients at risk,a no. | 192 | 181 | 180 | 177 | 157 | 146 |
| Hospital adminissions, no. | 59 | 17 | 15 | 9 | 4 | 3 |
| 24-Week hospitalization rate, % | 30.7 | 9.4 | 8.3 | 5.1 | 2.5 | 2.1 |
| Cause of hospitalization,b no. of admissions (%) | ||||||
| OI | 6 (10) | 0 | 0 | 0 | 0 | 0 |
| IRS | 17 (29) | 5 (29) | 2 (13) | 0 | 0 | 1 (33) |
| Drug-related adverse event | 3 (5) | 0 | 0 | 0 | 0 | 0 |
| Other infection | 32 (54) | 9 (53) | 11 (73) | 9 (100) | 3 (75) | 2 (67) |
| Noninfectious illness | 1 (2) | 3 (18) | 2 (13) | 0 | 1 (25) | 0 |
| Deaths, no. | 11 | 1 | 0 | 1 | 0 | 0 |
| 24-Week mortality rate, % | 5.7 | 0.6 | 0 | 0.6 | 0 | 0 |
NOTE. IRS, immune reconstitution syndrome; OI, opportunistic infection.
a
Number of patients decreased because of staggered enrollment.
b
Details are given in table 2.