Figure 2.

Murine p48 promoter constructs used in this study. (A) Constructs cloned into pGL3-basic vector. Selected restriction sites were indicated. Number of the last nucleotide from the +1 site was indicated on the left. Myc, binding site for myc/max; ΔM1, a deletion mutant that lacked GATE; pm, point mutant. The arrow shows the transcription start site. (B) Constructs prepared in pGL3 promoter vector, in which simian virus 40 early promoter drives the expression of luciferase gene. Sequences derived from p48 gene promoter are indicated with thick lines. Fold induction by IFN-γ is indicated on the right.