Table 3.
Comparison of Sensitivities, Specificities, and AUC for ORAI and SCORE Instrument to Predict BMD, T score ≤−2.5
| Sensitivity | Specificity | PPV | NPV | AUC | |
|---|---|---|---|---|---|
| ORAI | |||||
| Overall | 0.68 (0.49 to 0.88) | 0.66 (0.59 to 0.73) | 0.20 (0.11 to 0.29) | 0.94 (0.90 to 0.98) | 0.74 (0.63 to 0.84) |
| Non-Hispanic white | 0.60 (0.04 to 0.94) | 0.72 (0.57 to 0.81) | 0.17 (0.0 to 0.33) | 0.95 (0.86 to 1.0) | 0.76 (0.60 to 0.91) |
| Hispanic | 0.86 (0.47 to 0.99) | 0.59 (0.44 to 0.72) | 0.23 (0.07 to 0.39) | 0.97 (0.87 to 1.0) | 0.75 (0.59 to 0.91) |
| African American | 0.60 (0.34 to 0.91) | 0.67 (0.55 to 0.76) | 0.19 (0.05 to 0.32) | 0.93 (0.84 to 0.98) | 0.69 (0.52 to 0.87) |
| SCORE | |||||
| Overall | 0.54 (0.34 to 0.75) | 0.72 (0.65 to 0.78) | 0.19 (0.09 to 0.29) | 0.93 (0.89 to 0.97) | 0.67 (0.54 to 0.79) |
| Non-Hispanic white | 0.80 (0.27 to 0.98) | 0.63 (0.50 to 0.76) | 0.17 (0.01 to 0.34) | 0.97 (0.89 to 1.0) | 0.68 (0.44 to 0.93) |
| Hispanic | 0.71 (0.29 to 0.96) | 0.49 (0.35 to 0.63) | 0.17 (0.03 to 0.29) | 0.92 (0.78 to 0.99) | 0.69 (0.48 to 0.90) |
| African American | 0.30 (0.00 to 0.56) | 0.92 (0.86 to 0.98) | 0.33 (0.00 to 0.61) | 0.91 (0.85 to 0.97) | 0.70 (0.51 to 0.89) |
AUC, area under the receiver operator characteristic curve; NPV, negative predictive value; ORAI, osteoporosis risk assessment instrument; PPV, positive predictive value; SCORE, simple calculated osteoporosis risk estimation.