Table 2.
New Use of Antifracture Medications in 378 Older Female Health ABC Participants With a National Osteoporosis Foundation Indication for These Agents*
| Demographics and Socioeconomic Status | OR, Univariate | P Values, Univariate | OR, Multivariable† | P Values, Multivariable |
|---|---|---|---|---|
| White race | 3.6 (2.3 to 5.8) | <.001 | 2.6 (1.5 to 4.8)‡ | <.001 |
| Age, per y over 70 | – | – | 0.9 (0.9 to 1.0) | .21 |
| Income >25K | 2.0 (1.2 to 3.2) | .006 | 1.0 (0.6 to 1.8) | .98 |
| Drug coverage | 1.8 (1.1 to 2.8) | .02 | 1.6 (0.9 to 2.6) | .08 |
| Education ≥ HS | 2.3 (1.3 to 4.1) | .002 | 1.2 (0.6 to 2.4) | .55 |
| Health status and comorbid conditions | ||||
| Osteoporosis | 2.5 (1.6 to 3.9) | <.001 | 2.9 (1.7 to 4.7)‡ | <.001 |
| Charlson score ≥2 | 0.7 (0.4 to 1.3) | .28 | 1.0 (0.5 to 1.9) | .93 |
| Slow walking | 0.7 (0.5 to 1.2) | .23 | 1.0 (0.5 to 1.7) | .91 |
| Difficulty rising | 0.8 (0.4 to 1.5) | .49 | 0.7 (0.3 to 1.5) | .28 |
| Previous fracture | 1.2 (0.8 to 1.9) | .65 | 1.3 (0.8 to 2.1) | .40 |
| Fall/12 mo | 1.1 (0.6 to 1.7) | .90 | 1.1 (0.6 to 1.9) | .82 |
| 3MS score <80 | 0.3 (0.1 to 0.7) | .004 | 0.5 (0.2 to 1.5) | .24 |
| Medications >median | 1.3 (0.8 to 2.0) | .25 | 1.4 (0.9 to 2.4) | .17 |
| Self-efficacy and health behaviors | ||||
| Low self-efficacy | 1.0 (0.3 to 2.8) | 1.0 | 0.70 (0.2 to 2.3) | .55 |
| Received flu shot | 2.4 (1.5 to 3.9) | <.001 | 2.2 (1.3 to 3.8)‡ | .004 |
| Received mammogram | 0.9 (0.4 to 1.6) | .61 | 0.8 (0.4 to 1.7) | .52 |
*
Mean and standard deviation (SD) for all continuous variables. Odds ratios (OR) are presented with 95% confidence intervals.
†
For multivariable analysis, OR after adjustment for all other factors. The c-statistic for the model was 0.75.
‡
P <.05.
Health ABC, Health, Aging, and Body Composition; HS, high school, 3MS, Modified Mini-Mental State.