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Ribbon drawing of the three-dimensional model of the 8-fold mutated TLP-ste variant. The 55–69 region is shown in blue. The side chains for the amino acids that were mutated in this study (A4T, T56A, G58A, T63F, S65P, A69P) are shown in red and the disulfide bridge cross-linking residue 60 (N60C) in the critical region with residue 8 (G8C) in the underlying β-hairpin is shown in yellow. The light-blue sphere indicates the catalytic zinc ion.
