Table 2.
Definite |
Clinical presentation compatible with neurosarcoidosis |
Exclusion of other possible causes |
Positive nervous system histology |
Probable |
Clinical presentation compatible with neurosarcoidosis |
Laboratory support of CNS inflammation* |
Exclusion of other possible causes |
Evidence of systemic sarcoidosis† |
Possible |
Clinical presentation compatible with neurosarcoidosis |
Exclusion of other possible causes |
High concentration of CSF protein and high numbers of cells, the presence of oligoclonal bands, or MRI evidence compatible with neurosarcoidosis.
Positive histology or at least 2 indirect indicators from gallium scan, chest imaging, and serum angiotensin-converting-enzyme. Reproduced with permission from Oxford University Press.16
CNS, central nervous system; CSF, cerebrospinal fluid; MRI, magnetic resonance imaging