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. 1998 Mar 3;95(5):2061–2066. doi: 10.1073/pnas.95.5.2061

Figure 1.

Figure 1

(A) CBP stimulates activity of GATA-1(Δ63) in a dose-dependent manner using a synthetic reporter (M1α-GH). Numbers indicate amounts of transfected plasmid in μg. (B) CBP potentiates GATA-1(Δ63)-mediated activation of synthetic (M1α-GH) and natural (EKLF-GH) GATA-1 target promoters by with comparable efficiency. (C) CBP potentiates wtGATA-1 (Upper). wt E1A, but not E1AΔ2–36, inhibit CBP-mediated activation (Upper) without affecting expression of GATA-1 and CBP as determined by Western blot analysis (Lower).