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. 2007 Jun 22;7:107. doi: 10.1186/1471-2407-7-107

Table 2.

Rare allele carriage rates in breast cancer and controls

Groups Rare allele (A) carriage rate (%) Odds Ratio (95% CI) Test statistic (p value)#

Cancer Controls
Overall 136/846 (16.1%) 115/707 (16.3%) 0.99 (0.75–1.29) ×2 = 0.001; p = 0.97
Positive family history* 38/231 (16.5%) 22/153 (14.4%) 0.17 (0.66–2.07) ×2 = 0.16; p = 0.69
Negative family history* 98/615 (15.9%) 93/554 (16.8%) 0.94 (0.69–1.28) ×2 = 0.1; p = 0.75
Young patients** vs. controls 20/130 (15.4%) 115/707 (16.3%) 0.94 (0.56–1.57) ×2 = 0.01; p = 0.90

# Pearson's chi-square test (with Yates correction where applicable)

*Family history: either first or second-degree relative with breast cancer

**Young cancer patients: </= 50 years of age