Table 3.

Rare allele carriage rates in subgroups of invasive breast cancer

Tumour Severity		Rare allele carriage rates (%)	Test statistic (p value)#
Tumour size	Less than 2 cm	68/414 (16.4%)	p = 0.94$
	2 to 5 cm	42/270 (15.6%)
	More than 5 cm	2/17 (11.8%)
Tumour Grade	Grade 1	28/149 (18.8%)	×2 = 1.99; p = 0.37
	Grade 2	57/329 (17.3%)
	Grade 3	33/239 (13.8%)
Nodal Invasion	Absent	82/498 (16.5%)	×2 = 0.23; p = 0.63
	Present	40/219 (18.3%)
Vascular invasion	Absent	86/515 (16.7%)	×2 = 1.06; p = 0.30
	Present	17/135 (12.6%)
Oestrogen Receptor Status	Present	48/264 (18.2%)	×2 = 0.91; p = 0.34
	Absent	13/98 (13.3%)

# Pearson's chi-square test (with Yates correction where applicable)

^$ Fisher's exact test.