Table II.
Characteristics of women in the Collaborative Perinatal Project and their association with time to pregnancy. Women in the Collaborative Perinatal Project were enrolled at 12 study centers in the United States from 1959–1965.
Characteristic | All Women (N=7327)
|
Time to pregnancy ≤ 3 months (n=3801)
|
Time to pregnancy> 3 months (n=3526)
|
Age-Adjusted Fecundability Odds Ratio† |
|
---|---|---|---|---|---|
% or Median(Q1, Q3) ‡ | % or Median (Q1, Q3) | % or Median (Q1, Q3) | FOR | 95% CI | |
Prepregnancy BMI* | 21.4 (19.6, 23.7) | 21.2 (19.6, 23.3) | 21.8 (19.8, 24.2) | ||
Under-weight | 12 | 12 | 12 | 0.94 | 0.86, 1.03 |
Optimal weight | 71 | 73 | 69 | 1 | -- |
Over-weight | 13 | 11 | 14 | 0.84 | 0.77, 0.92 |
Obese | 5 | 4 | 5 | 0.72 | 0.63, 0.83 |
Median Age (years) | 23 (20, 27) | 22 (20, 26) | 24 (21, 28) | 0.95 | 0.94, 0.96 |
Smokers (%) | 45 | 44 | 47 | 0.91 | 0.86, 0.96 |
Race (%) | |||||
White | 63 | 68 | 57 | 1 | -- |
Non-white | 37 | 32 | 43 | 0.65 | 0.62, 0.70 |
Prior Pregnancies (%) | |||||
0 | 36 | 39 | 33 | 1 | -- |
1 | 30 | 31 | 30 | 0.98 | 0.91, 1.05 |
2+ | 34 | 30 | 37 | 1.04 | 0.97, 1.13 |
Prior Miscarriage | |||||
0 | 79 | 82 | 77 | 1 | -- |
1 | 15 | 14 | 17 | 0.96 | 0.88, 1.04 |
2+ | 6 | 4 | 6 | 0.97 | 0.86, 1.11 |
Irregular cycles (%) | 8 | 7 | 9 | 0.82 | 0.74, 0.91 |
Occupation (%) | |||||
Never worked | 12 | 12 | 13 | 1 | -- |
White collar | 44 | 49 | 39 | 1.47 | 1.34, 1.61 |
Blue collar | 44 | 39 | 48 | 1.02 | 0.93, 1.11 |
Education | |||||
Elementary | 16 | 12 | 19 | 0.44 | 0.40, 0.49 |
Less than HS | 33 | 32 | 33 | 0.54 | 0.49, 0.59 |
HS | 33 | 33 | 33 | 0.63 | 0.58, 0.68 |
More than HS | 19 | 23 | 14 | 1 | -- |
BMI = body mass index; categorized into underweight (<18.5 kg/m2), normal weight (18.5 kg/m2–24.9 kg/m2), overweight (25.0 kg/m2–29.9 kg/m2), and obese (≥30.0 kg/m2).
Cox discrete time survival analysis used to model time-to-pregnancy, fecundability odds ratios and 95 percent (%) confidence interval (CI) reported
% = percent, Q1 = quartile 1, Q3 = quartile 3, FOR = fecundability odds ratio, CI = confidence interval