Table 2.

Adjusted Rate Ratios for Skin Lesions by Quintile of Blood Selenium Level

					Model 1		Model 2
Blood Se Quintile (μg/L)	Mean Blood Se Level (μg/L)	No. of subcohort (%)	No. of cases (%)	Age- & Sex-adjusted Rate Ratios (95% CI) *	No. of subcohort/cases	Multivariate Adjusted Rate Ratios (95% CI) †	No. of subcohort/cases	Multivariate Adjusted Rate Ratios (95% CI) ‡
68.8–132.4	121.0	170 (20.0)	72 (23.8)	1.00	168/72	1.00	158/68	1.00
132.5–145.0	139.0	173 (20.4)	62 (20.5)	0.81 (0.49–1.34)	172/60	0.68 (0.39–1.18)	160/58	0.60 (0.33–1.10)
145.1–156.6	150.7	167 (19.7)	52 (17.2)	0.58 (0.35–0.96)	166/51	0.51 (0.29–0.87)	156/50	0.52 (0.30–0.89)
156.7–169.8	163.4	171 (20.1)	59 (19.5)	0.62 (0.37–1.04)	169/58	0.52 (0.30–0.91)	157/57	0.53 (0.30–0.96)
169.9–262.6	187.3	168 (19.8)	58 (19.0)	0.56 (0.33–0.93)	167/58	0.53 (0.31–0.90)	160/55	0.51 (0.29–0.89)

^*Rate Ratios were adjusted for age and sex

^†Rate Ratios were adjusted for age, sex, BMI, smoking status, and baseline well As. A total of 11 subjects with unknown BMI were excluded from the analysis

^‡Rate Ratios were adjusted for age, sex, BMI, smoking status, baseline well As, well switching status at follow-up, urinary As at follow-up, excessive sunlight exposure in men, total energy intake, and dietary intakes of folate, iron, protein, Vitamin E, B2, B12, and B6. A total of 83 subjects with unknown information on BMI, well switching status since baseline, urinary As level at the time of follow-up, or dietary intakes of As-related nutrients were excluded from the analysis