Table 1.

Worm Burden in S mansoni—Infected Mice Treated With BDHQ and PZQ vs Infected Untreated Control Group

Animal Group	Drug Dose	Mean Worm Burden ± SD	Immature
Group I (n = 10)	_	31.4 ± 0.85	36 ± 1.41
Group II (n = 10)	2 × 0.5 mL	8.7 ± 1.11*	20 ± 4.10†
Group III (n = 10	2 × 1 mL	4.1 ± 0.67*	20 ± 4.10†
Group IV (n = 10)	2 × 500 mg/kg	1.22 ± 0.72*	34.5 ± 4.5

^*Highly significant difference from group 1 (P < .001)

^†Significant reduction from groups 1 and IV (P < .05)