Table 3.
AMB Period vs. AZ Period | AZ Period | ||||
AMB Period (n = 259) | AZ Period (n = 321) | p-value1 | FLU (n = 237) | VOR (n = 84) | |
Mean Total | $44,129 | $53,257 | 0.0141 | $42,350 | $66,975 |
Costs2 | ($39,643–$49,122) | ($47,834–$59,296) | ($37,952–$47,257) | ($55,892–$80,255) | |
Mean Pharm | $10,361 | $19,751 | <0.0001 | $12,009 | $32,484 |
Costs2 | ($9,043–$11,871) | ($17,229–$22,642) | ($10,447–$13,805) | ($25,792–$40,911) | |
Mean Lab | $438 | $506 | 0.02 | $467 | $548 |
Costs2 | ($402–$477) | ($464–$552) | ($427–$510) | ($473–$636) |
1p-values are from mixed effects logistic regression models that controlled for the number of hospitalizations. P-values reflect the comparison of the cost in the AZ period relative to the cost in the AMB period
2Reported means are least squared means from mixed effects regression models that controlled for the number of hospitalizations
All costs are rounded to the nearest dollar. All costs are means (lower 95% confidence interval to upper 95% confidence interval)
Note: AMB = Amphotericn; AZ = Azole; FLU = flunconazole; VOR = voriconazole; Pharm = pharmacy; Lab = Laboratory.