Table 4.
Total, median, and mean acquisition cost of antifungals (US Dollars)
| AMB Period (n = 255)1 | AZ Period (n = 317)1 | |||||||
| n2 | Total Cost3 | Median Cost4 | Mean Cost4 | n2 | Total Cost3 | Median Cost4 | Mean Cost4 | |
| AMB | 254 | $119,194 | $70 ($65–$76) | $467 ($274–$661) | 198 | $36,129 | $18 ($9–$27) | $113 ($40–$186) |
| FLU | 33 | $8,343 | 0 | $29 ($2–$56) | 228 | $78,849 | $173 ($108–$224) | $245 ($211–$278) |
| VOR | 4 | $10,485 | 0 | $34 ($0–$76) | 160 | $216,559 | $75 (0–$250) | $682 ($563–$802) |
| CASPO | 7 | $17,228 | 0 | $66 ($11–$122) | 43 | $174,718 | 0 | $537 ($333–$741) |
| ITRA | 50 | $7,984 | 0 | $29 ($19–$40) | 6 | $833 | 0 | $3 ($0–$5) |
| Total | 348 | $164,405 | $70 | $630 | 645 | $507,175 | $266 | $1,577 |
1Number of hospitalizations with available charges
2Number of hospitalizations with charges for the individual antifungals
3All costs are rounded to the nearest dollar
4Median or mean cost (lower 95% confidence interval to upper 95% confidence interval). Reported means are least squared means from mixed effects regression models that controlled for the number of hospitalizations
Note: AMB = amphotericin; AZ = Azole; FLU = fluconazole; VOR = voriconazole; CASPO = caspofungin; ITRA = itraconazole