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. 2007 Jun 28;8:197. doi: 10.1186/1471-2164-8-197

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Copyright © 2007 Kobayashi et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Outline of procedure for elucidating TUs by integrated analyses. (1) Co-expressed gene clusters predicted by correlating expression profiles between neighboring genes; (2) promoter (thin arrows) prediction by PWM as the start of a TU in the putative co-expressed gene clusters; (3) detection of significantly expressed genes (stripe thick arrows) by comparison between TF deletion mutant arrays and wild ones; (4) identification of genes composing putative TUs (filled thick arrows) by integration of the three analyses.