Table 3.

Cost* and other data summarized

	Base case (range)	Reference
Celecoxib 200 mg/d	$2.64 ($2.11–$3.17)	http://drugstore.com
Naproxen 1000 mg/d	$0.45 ($0.36–$0.54)	http://drugstore.com
Diclofenac 100 mg/d	$0.64 ($0.51–$0.77)	http://drugstore.com
Omeprazole (over-the-counter) 20 mg/d	$0.60 ($0.48–$0.72)	http://drugstore.com
Price reduction generic celecoxib	55% (30%–80%)	[61,63]
POB inpatient-hospital plus physician (ALOS = 5.56 days)	$12,796 ($10,234–$15,355)	[12,40]
POB outpatient-hospital plus physician	$1,813 ($1,450–$2,176)	[12,160,161]
Peptic ulcer inpatient-hospital plus physician (ALOS = 4.10 days)	$7,353 ($5,882–$8,824)	[12,40]
Peptic ulcer outpatient discrete event including endoscopy	$1,554 ($1,243–$1,865)	[12,160,161]
Dyspepsia outpatient initial event including endoscopy	$1,208 ($966–$1,450)	[12,160,161]
Ongoing annual medical and laboratory costs chronic peptic ulcer or dyspepsia	$130 ($104–$156)	[160], Estimates RBRVS
POB proportion of surgery DRGs	14.2%	[40]
POB admissions through emergency	89.7%	[40]
Proportion of peptic ulcer patients admitted to hospital	4.37%	[40]
Discount rate for costs and QALYs	3.0%
Price inflation rate	2.0%

POB, perforation, obstruction, bleeding ulcer; ALOS, average length of stay; RBRVS, resource-based relative value scale; DRGs, diagnosis-related groups. *Drug prices as of February 2006.