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. 2007 Jul 24;5(8):e201. doi: 10.1371/journal.pbio.0050201

Figure 4. Up-Regulation of P-selectin Cell Surface Expression and NF-κB Localization in Aged HSCs.

Figure 4

(A) An increasing percentage of HSCs express P-selectin (SelP) when examined by FACS, ranging from 3% (2-mo-old HSCs) to 81% (28-mo-old HSCs). FITC, fluorescein isothiocyanate; PE, phycoerythrin.

(B and C) HSCs stained with anti-p65 NF-kB antibody (red) and DAPI (blue). Two-month-old HSCs contain approximately 3% nuclear-localized p65; however, at 22 mo, approximately 71% show nuclear-localized p65.