Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
| Variants | Method | ||
| SIFT | PANTHER | PolyPhen | |
| p.Ser75Phe | − | − | − |
| p.Asn102Ser | + | + | − |
| p.Asp112Gly | + | + | + |
| p. Arg119Gly | + | − | + |
| p.Thr175Ile | + | + | + |
| p.Asn232Ser | + | − | + |
Sequence homology for SIFT prediction was calculated with the alignment of orthologs selected from Eukaryota. ‘−’ and ‘+’ indicate the predicted benign and deleterious effects of the mutations, respectively.
