Table 2.

Metabolic characteristics by diagnosis and Pro12Ala genotype.

	Controls			PCOS
	C/C	C/G or G/G	P-Values	C/C	C/G or G/G	P-Values
	n=72	n=22		N=148	n=40
Age (yr)	34.8 ± 13.1	40.6 ± 12.4	0.032	27.1 ± 7.2	27.0 ± 7.7	0.84
Body mass index (kg/m2)	26.9 ± 6.5	25.4 ± 5.7	0.13	35.9 ± 8.8	36.6 ± 10.2	0.64
Fasting Insulin [μIU/mL	9.7 ± 7.3	6.8 ± 3.7	0.094	20.5 ± 15.4	24.3 ± 17.8	0.54
(pmol/L)]	(69.7 ± 52.7)	(48.9 ± 26.4)		(147.2 ± 110.6)	(174.5 ± 127.9)
Fasting Glucose [mg/dL	87.0 ± 11.3	87.4 ± 9.7	0.67	88.0 ± 10.6	87.8 ± 11.4	0.93
(mmol/L)]	(4.83 ± 0.63)	(4.85 ± 0.54)		(4.88 ± 0.59)	(4.87 ± 0.63)
HOMA-IR	1.30 ± 0.97	0.94 ± 0.49	0.10	2.31 ± 1.36	2.74 ± 1.68	0.43
HOMA-%B	118.9 ± 51.4	93.4 ± 30.3	0.13	177.5 ± 84.2	200.8 ± 101.8	0.39

Note: Comparisons are made between the 2 genotypes within each group, using logistic regression (hirsutism) or analysis of covariance (other traits). Multiple testing-corrected P value<0.01 is significant. Values are mean ± SD.