Table 1.
Mu1 and Mu11 have the same respective Kd for binding Man-BSA and S4GGnM-BSA as does the wild-type Man/S4GGnM-Fc chimera
| Oligosaccharide | Man/S4GGnM-Fc chimera, mean ± SE
|
||
|---|---|---|---|
| Wt | Mu1 | Mu11 | |
| Man-BSA | |||
| Kd | 4.4 ± 1.1 × 10−9 M | 3.1 ± 1.5 × 10−9 M | |
| S4GGnM-BSA | |||
| Kd | 11.9 ± 3.4 × 10−9 M | 13.2 ± 3.9 × 10−9 M | |
The results of nonlinear regression analyses of the saturation experiments shown in Fig. 3 are summarized. Additional saturation studies performed with independently prepared batches of each chimera yielded similar results. The standard error (SE) is indicated.