Figure 7.

CBP rescues RelA-mediated repression of AR function. CV-1 cells were transfected with pARE₄tk-LUC reporter (5 μg) and indicated amounts (in μg) of pCMV-hAR, pCMV-RelA, and pSG5-CBP vectors in the absence or presence of 25 nM testosterone (T) as indicated. The cells were treated and harvested as described in Fig. 1. LUC activities are expressed relative to that of human AR plus testosterone, and data are the mean ± SEM of two experiments.