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Limited nuclease digestion of full-length transcript of Rz13/40. Letters in filled circles indicate the following: A, cleavage with RNase A; S, with nuclease S1; T, with RNase T1; t, weak cleavage with RNase T1; and a, weak cleavage with RNase A. Nucleotide symbols in open circles, positions different from conventional hammerhead ribozyme; empty circles, position not occupied in Rz13/40.
