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. Author manuscript; available in PMC: 2007 Dec 1.
Published in final edited form as: Biochem Biophys Res Commun. 2006 Oct 6;350(4):1063–1068. doi: 10.1016/j.bbrc.2006.09.158

Figure 1. Phenotypic characteristics of JNK1 knockout mice.

Figure 1.

(A) At all ages studied, JNK1 knockout mice had significantly lower body weights compared to wild‐type controls (N = 15–26 mice). (B) Following a 12 hr fast, blood glucose levels were significantly lower in JNK1 knockout mice at age ≥16 weeks compared to wild‐type control mice (N = 18–26 mice). (C) Following an intravenous injection of glucose (1 mg glucose / g mouse body weight), blood glucose levels decreased faster in JNK1 knockout mice. Glucose tolerance, assessed as the rate of decline following the glucose bolus, was enhanced by JNK1 deficiency (N = 3–5 mice/group). (* = P<0.05 vs wild‐type)