Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Multicomponent closed-time distributions of the IP3R channel result in “burst-like” behavior. (A) Closed-time distributions at [Ca2+] = 0.2, 2.0, and 50 μM for [IP3] = 10 μM. Open symbols are stochastic simulations and solid curves are from the transition matrix theory. (B) Two examples of the fluctuation in average channel open probability within a 100-m-running window, respectively, for [Ca2+] = 0.1 and 100 μM and [IP3] = 10 μM.
