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. 2007 May 25;93(4):1151–1162. doi: 10.1529/biophysj.107.108795

FIGURE 6.

FIGURE 6

Distributions of first-opening latencies for a single IP3R after different steps of [IP3] at various [Ca2+]. (A) Three examples are shown of stochastic simulations for a step of [IP3] from 0 to 10 μM (lower) with [Ca2+] = 0.1 μM. (B and C) Distributions of first-opening latencies after stepwise increases in [IP3] derived from stochastic modeling (open symbols) and theory (solid lines). Results are plotted for different magnitudes of Inline graphic with [Ca2+] = 0.1 μM (B), and for different [Ca2+] with Inline graphic = 10 μM (C).