Figure 3.

Adhesion of IOSE29, HEY and OVHS1 cell lines grown as monolayer versus spheroids on different ECM. The adhesive response of cells grown as monolayer or as spheroids (day 2) on CI, FN and LM was determined as described in the Materials and Methods. Experiments on HEY and OVHS1 cells were repeated at least three times and performed in triplicate. The experiment on IOSE29 cell line was repeated twice. Results are representative of one experiment performed in triplicate, *significantly different from cells growing as a monolayer, p < 0.05.