Figure 3.

Ectopic expression of the hGH transgene in skin does not alter epidermal morphology. (A and B) Backskin sections from an adult line 22 K14–hGH expressing mouse (A) and a control littermate (B) were subjected to in situ hybridization with an antisense digoxygenin-labeled hGH cRNA. (C and D) Tailskin sections from an adult transgenic (C) and control (D) mouse were stained with hematoxylin/eosin. Note that the epidermis of backskin, with abundant hair follicles, is thinner than that of tailskin, with few follicles. (Bar = 90 μm in A and B, and 45 μm in C and D.)