Table 2.
Genes upregulated by AI treatment
| ID | Symbol | Description | Unigene | Fold | LFDR |
| HSI022G08 | LUM | Lumican | Hs.406475 | 2.87 | 0.11 |
| HSI101E05 | ODF2L | Outer dense fiber of sperm tails 2-like | Hs.149360 | 2.80 | 0.07 |
| HSI027H04 | IGJ | Immunoglobulin J polypeptide | Hs.381568 | 2.73 | 0.07 |
| HSI082D05 | RNH1 | Ribonuclease/angiogenin inhibitor 1 | Hs.530687 | 2.51 | 0.00 |
| HSI056B04 | COL3A1 | Collagen, type III, alpha 1 | Hs.443625 | 2.50 | 0.00 |
| HSI182D05 | MRC1L1 | Mannose receptor, C type 1 | Hs.461247 | 2.45 | 0.06 |
| HSI067F08 | C21orf70 | Chromosome 21 open reading frame 70 | Hs.410830 | 2.44 | 0.00 |
| HSI127E04 | CALD1 | Caldesmon 1 | Hs.490203 | 2.37 | 0.11 |
| HSI030C06 | PTPRC | Protein tyrosine phosphatase, receptor type, C | Hs.192039 | 2.36 | 0.11 |
| HSI067H02 | ASPN | Asporin (LRR class 1) | Hs.435655 | 2.34 | 0.00 |
| HSI066B08 | COL14A1 | Collagen, type XIV, alpha 1 (undulin) | Hs.409662 | 2.28 | 0.11 |
| HSI049B12 | COL1A2 | Collagen, type I, alpha 2 | Hs.489142 | 2.28 | 0.00 |
| HSI049G07 | DCN | Decorin | Hs.156316 | 2.28 | 0.00 |
| HSI067E05 | MRC1L1 | Mannose receptor, C type 1 | Hs.461247 | 2.22 | 0.05 |
| HSI101D05 | IFT122 | Intraflagellar transport 122 homolog (Chlamydomonas) | Hs.477537 | 2.17 | 0.03 |
| HSI183E05 | PDGFRA | Platelet-derived growth factor receptor, alpha | Hs.74615 | 2.14 | 0.09 |
| HSI031A12 | FSTL1 | Follistatin-like 1 | Hs.269512 | 2.12 | 0.00 |
| HSI183H01 | COL5A2 | Collagen, type V, alpha 2 | Hs.445827 | 2.11 | 0.00 |
| HSI055A11 | ECM2 | Extracellular matrix protein 2 | Hs.117060 | 2.08 | 0.09 |
| HSI018G02 | SPON1 | Spondin 1, extracellular matrix protein | Hs.445818 | 2.06 | 0.00 |
| HSI183B01 | PDGFRA | Platelet-derived growth factor receptor, alpha | Hs.74615 | 2.04 | 0.01 |
| HSI037C02 | CPVL | Carboxypeptidase, vitellogenic-like | Hs.233389 | 2.03 | 0.06 |
| HSI062B08 | SAS10 | Disrupter of silencing 10 | Hs.322901 | 2.01 | 0.00 |
| HSI129E10 | ADAM12 | ADAM metallopeptidase domain 12 (meltrin alpha) | Hs.386283 | 2.00 | 0.00 |
| HSI183G08 | RGS1 | Regulator of G-protein signalling 1 | Hs.75256 | 1.98 | 0.18 |
| HSI054F01 | VIM | Vimentin | Hs.533317 | 1.97 | 0.00 |
| HSI048C08 | CTGF | Connective tissue growth factor | Hs.410037 | 1.97 | 0.00 |
| HSI183G05 | SPARC | Secreted protein, acidic, cysteine-rich (osteonectin) | Hs.111779 | 1.96 | 0.00 |
| HSI139G09 | ADAMTS2 | ADAM metallopeptidase with thrombospondin motif 2 | Hs.23871 | 1.96 | 0.00 |
| HSI018D05 | FBLN1 | Fibulin 1 | Hs.24601 | 1.95 | 0.00 |
| HSI040E08 | DUSP1 | Dual specificity phosphatase 1 | Hs.171695 | 1.95 | 0.00 |
| HSI082C05 | MAN1A1 | Mannosidase, alpha, class 1A, member 1 | Hs.102788 | 1.94 | 0.01 |
| HSI098G12 | RARRES1 | Retinoic acid receptor responder 1 | Hs.131269 | 1.94 | 0.00 |
| HSI044C09 | SAT | Spermidine/spermine N1-acetyltransferase | Hs.28491 | 1.92 | 0.09 |
| HSI030F05 | HTRA1 | HtrA serine peptidase 1 | Hs.501280 | 1.92 | 0.00 |
| HSI088D11 | CILP | Cartilage intermediate layer protein | Hs.442180 | 1.91 | 0.00 |
| HSI040E09 | MME | Membrane metallo-endopeptidase (CALLA, CD10) | Hs.307734 | 1.91 | 0.00 |
| HSI028G12 | PDGFRA | Platelet-derived growth factor receptor, alpha | Hs.74615 | 1.89 | 0.00 |
| HSI060C05 | FN1 | Fibronectin 1 | Hs.203717 | 1.89 | 0.00 |
| HSI045G12 | CXCL12 | Chemokine ligand 12 (stromal cell-derived factor 1) | Hs.522891 | 1.88 | 0.00 |
Shown are the first 40 upregulated genes from a paired SAM analysis, which identified 1,365 genes to be upregulated by aromatase inhibitor (AI) treatment below a local false discovery rate of 1% (LFDR). The genes are ranked according to their fold change.