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. 2007 May 1;8(5):R69. doi: 10.1186/gb-2007-8-5-r69

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Copyright © 2007 Fodor et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Estimates of standard error do not survive quantile-quantile normalization. (a,b) ${\bar{x}}_{1} - {\bar{x}}_{2}$ (panel a) and σ²(panel b) before and after background correction and quantile-quantile normalization for the comparison of the Latin Square experiments 1 and 2. Fits shown are to a linear regression. (c) Box plot showing the R²values from a linear fit for all 14 2× Latin Square comparisons.