Table 3.
Genes related to oligodendrocyte differentiation are differentially expressed in Nfia-/- mice at P16
| Gene name | Fold change of mRNA expression in Nfia-/- versus Nfia+/+ micea | Reference |
| Genes typically expressed in oligodendrocyte precursors or related to de-differentiation of precursor cells | ||
| Hmgb2 | 1.92 | [45] |
| Sox2 | 1.28 | [46] |
| Sox4 | 1.33/1.44 | [47] |
| Sox11 | 1.88/2.22 | [47] |
| Tenascin-C | 1.47 | [48] |
| Myef2b | 1.2 | [39] |
| Genes typically expressed in mature oligodendrocytes or related to terminal oligodendrocyte differentiation | ||
| Mobp | -2.11/-2.10/-1.99/-1.98 | [49] |
| Mal | -2.43 | [50] |
| Mog | -1.95 | [51] |
| Claudin 11 | -1.67 | [52] |
| Plp1 | -1.58 | [53] |
| Ugt8 | -1.54/-1.45 | [50] |
| Mag | -1.52 | [53] |
| Dio2c | -1.43 | [38] |
| Car2 | -1.35 | [54] |
aAccording to microarray analysis; for genes represented by more than one probe set, the individual fold changes for each probe set are given. bIndirect link to oligodendrocyte maturation (My-EF2 can repress expression of myelin basic protein). cIndirect link to oligodendrocyte maturation (Dio2 catalyzes thyroxine to tri-iodothyronine conversion, and tri-iodothyronine triggers terminal differentiation of oligodendrocytes). P16, postnatal day 16.