Table 5.
Human-opossum TFBS conservation dependency on transcription factor identity
| Factor | Motif | Human versus opossum | ||||
| IC | Length | Detectable | % conserved | p value | Over/under | |
| HMG | 8.43 | 9 | 7 | 100.00% | 0.0020 | Over* |
| p50 | 15.63 | 11 | 8 | 75.00% | 0.0470 | Over |
| MITF | N/A | N/A | 10 | 70.00% | 0.0487 | Over |
| CREB | 11.52 | 8 | 13 | 69.23% | 0.0287 | Over |
| E2F-1 | 10.17 | 8 | 10 | 60.00% | 0.1228 | |
| GR | 7.06 | 6 | 7 | 57.14% | 0.2056 | |
| HNF-1α | N/A | N/A | 7 | 57.14% | 0.2056 | |
| POU1F1a | 7.57 | 5 | 9 | 55.56% | 0.1794 | |
| E2F | 13.84 | 8 | 11 | 54.55% | 0.1594 | |
| AP-1 | 9.44 | 7 | 24 | 50.00% | 0.1112 | |
| ATF-2 | N/A | N/A | 8 | 50.00% | 0.2422 | |
| USF1 | 10.37 | 6 | 8 | 50.00% | 0.2422 | |
| IPF1 | N/A | N/A | 9 | 44.44% | 0.2565 | |
| HIF-1 | 11.00 | 11 | 7 | 42.86% | 0.2938 | |
| p53 | 25.74 | 18 | 16 | 37.50% | 0.1949 | |
| HNF-1α-A | 13.66 | 10 | 8 | 37.50% | 0.2763 | |
| NF-κB | 13.34 | 10 | 11 | 36.36% | 0.2321 | |
| Sp1 | 9.22 | 8 | 86 | 29.07% | 0.0049 | Under |
| AP-2αA | N/A | N/A | 23 | 26.09% | 0.0581 | |
| C/EBPα | 11.12 | 9 | 16 | 25.00% | 0.0886 | |
| Egr-1 | 13.12 | 9 | 8 | 25.00% | 0.1961 | |
| c-Myb | 14.15 | 11 | 11 | 18.18% | 0.0775 | |
| ER-α | N/A | N/A | 9 | 11.11% | 0.0521 | |
| GATA-1 | 5.57 | 4 | 9 | 11.11% | 0.0521 | |
| Gfi1 | 7.60 | 4 | 11 | 0.00% | 0.0028 | Under |
| AhR | 8.62 | 6 | 7 | 0.00% | 0.0238 | Under |
| TCF-4 | 12.54 | 7 | 7 | 0.00% | 0.0238 | Under |
See Table 5 footnote for details.