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. 1998 Mar 3;95(5):2198–2203. doi: 10.1073/pnas.95.5.2198

Table 1.

IC50 values for daidzin and its structural analogs on the rate of 5-HIAA and DOPAC formation catalyzed by intact hamster and rat liver mitochondria

Compounds IC50, μM
Hamster
Rat
5-HIAA DOPAC 5-HIAA DOPAC
Deczein 0.06 0.09 0.05 0.06
Hepzein 0.13 0.3 0.15 0.2
Hexzein 0.21 0.7 0.5 0.4
Daidzin 2.7 2.5 2.0 2.1
Daidzein 11 10 9 10
Puerarin n.i. n.i. 30 28
Dicarboxymethyl-daidzein n.i. n.i. n.i. n.i.

For methods, see legends of Figs. 3 and 5. n.i., no inhibition up to 30 μM.