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Pioglitazone induces differentiation of cultured human liposarcoma cells. Primary LS857 (A and B) and LS707 (C and D) cells were isolated and cultured in 60-mm dishes. At confluence, cells were cultured for 7 days in the presence (B and D) or absence (A and C) of 10 μM pioglitazone. After an additional 4 days of culture, cells were fixed and stained with oil red O. (×40.)
