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Induction of differentiation in human liposarcoma cells by thiazolidinediones and RXR-specific retinoids. LS857 cells were treated at confluence for 7 days with no activator, 5 μM thiazolidinedione (BRL 49653 or pioglitazone), 50 nM LG268, or both as indicated. After an additional 4 days of culture cells were fixed and stained with oil red O. Macroscopic view of the 60-mM culture dishes is shown.
