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. Author manuscript; available in PMC: 2007 Jul 22.
Published in final edited form as: Surv Ophthalmol. 2006;51(1):41–50. doi: 10.1016/j.survophthal.2005.11.002

TABLE 1.

Summary of Characteristics of Primary Testicular Lymphoma and Primary Intraocular Lymphoma

Primary Lymphoma
Testis Eye (Retina/Vitreous)
Immunoprivileged Site Yes Yes
Incidence among all non-Hodgkin Lymphomas 1% 0.2%
Clinical presentation Painless mass in older man (usually unilateral) Masquerade uveitis in elder people (frequent bilateral)
Morphology Predominantly (68%) diffuse large B-cell; 30% small non-cleaved cell26,63,71 Mostly diffuse large B-cell lympoma48
Metastases
 CNS 6–16.5% 60–80%
 Vitreous One reported case19 —
 Uvea One reported case26 Rare15,50,57,65,66
 Orbit Three reported cases26,37,44 Extremely rare*
 Testis — None reported
*

From our experience at the NEI, only 1 in 72 cases involved the orbit; this case is an AIDS-associated PIOL.